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BDBM50438794 CHEMBL2413224

SMILES: COc1ccc(cc1)C(=O)c1cccn1-c1cnn(O)c1

InChI Key: InChIKey=VYNLJRDBKHRAEM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438794   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Rattus norvegicus)
BDBM50438794
PNG
(CHEMBL2413224)
Show SMILES COc1ccc(cc1)C(=O)c1cccn1-c1cnn(O)c1
Show InChI InChI=1S/C15H13N3O3/c1-21-13-6-4-11(5-7-13)15(19)14-3-2-8-17(14)12-9-16-18(20)10-12/h2-10,20H,1H3
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Aristotle University of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of partially purified Fischer-344 rat kidney ALR1 using D,L-glycuronate as substrate assessed as NADPH consumption by spectrophotometry


Bioorg Med Chem 21: 4951-7 (2013)


Article DOI: 10.1016/j.bmc.2013.06.062
BindingDB Entry DOI: 10.7270/Q28S4RCK
More data for this
Ligand-Target Pair