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BDBM50439118 CHEMBL2418073

SMILES: O=c1[nH]c(=S)[nH]c2nc(nn12)-c1ccc(cc1)C#N

InChI Key: InChIKey=IONPGRLTJYTHML-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439118   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thymidine Phosphorylase (TP)


(Homo sapiens (Human))
BDBM50439118
PNG
(CHEMBL2418073)
Show SMILES O=c1[nH]c(=S)[nH]c2nc(nn12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C11H6N6OS/c12-5-6-1-3-7(4-2-6)8-13-9-14-10(19)15-11(18)17(9)16-8/h1-4H,(H2,13,14,15,16,18,19)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 3.31E+4n/an/an/an/an/an/a



National University of Singapore

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thymidine phosphorylase expressed in Escherichia coli using thymidine as substrate after 4 to 20 mins by spectrophoto...


Eur J Med Chem 67: 325-34 (2013)


Article DOI: 10.1016/j.ejmech.2013.06.051
BindingDB Entry DOI: 10.7270/Q2QR4ZJ0
More data for this
Ligand-Target Pair