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BDBM50439128 CHEMBL2418063

SMILES: Cc1cccc(c1)-c1nc2[nH]c(=S)[nH]c(=O)n2n1

InChI Key: InChIKey=XNCBGRWLRPTELM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439128   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thymidine Phosphorylase (TP)


(Homo sapiens (Human))
BDBM50439128
PNG
(CHEMBL2418063)
Show SMILES Cc1cccc(c1)-c1nc2[nH]c(=S)[nH]c(=O)n2n1
Show InChI InChI=1S/C11H9N5OS/c1-6-3-2-4-7(5-6)8-12-9-13-10(18)14-11(17)16(9)15-8/h2-5H,1H3,(H2,12,13,14,15,17,18)
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Similars

Article
PubMed
n/an/a 3.44E+4n/an/an/an/an/an/a



National University of Singapore

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thymidine phosphorylase expressed in Escherichia coli using thymidine as substrate after 4 to 20 mins by spectrophoto...


Eur J Med Chem 67: 325-34 (2013)


Article DOI: 10.1016/j.ejmech.2013.06.051
BindingDB Entry DOI: 10.7270/Q2QR4ZJ0
More data for this
Ligand-Target Pair