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BDBM50439136 CHEMBL2418081

SMILES: O=c1[nH]c2nc(Cc3ccccc3)nn2c(=O)[nH]1

InChI Key: InChIKey=PCYOLXSEEPZFSV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439136   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thymidine Phosphorylase (TP)


(Homo sapiens (Human))
BDBM50439136
PNG
(CHEMBL2418081)
Show SMILES O=c1[nH]c2nc(Cc3ccccc3)nn2c(=O)[nH]1
Show InChI InChI=1S/C11H9N5O2/c17-10-13-9-12-8(15-16(9)11(18)14-10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,12,13,14,15,17,18)
PDB
MMDB

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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



National University of Singapore

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thymidine phosphorylase expressed in Escherichia coli using thymidine as substrate after 4 to 20 mins by spectrophoto...


Eur J Med Chem 67: 325-34 (2013)


Article DOI: 10.1016/j.ejmech.2013.06.051
BindingDB Entry DOI: 10.7270/Q2QR4ZJ0
More data for this
Ligand-Target Pair