BDBM50439314 CHEMBL2419508

SMILES O=C(NCc1ccc(cc1)S(=O)(=O)c1ccccc1)N1Cc2ccccc2C1

InChI Key InChIKey=HVOYCRDUPXJFLU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439314   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50439314(CHEMBL2419508)
Affinity DataKi:  487nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50439314(CHEMBL2419508)
Affinity DataIC50:  12nMAssay Description:Inhibition of human NAMPT using NAM/PRPP as substrate incubated for 15 mins prior to substrate addition measured after 30 mins by mass spectrometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed