BindingDB logo
myBDB logout

BDBM50439391 CHEMBL2420401

SMILES: COC(=O)c1c(NC(=O)CSc2ccc(Br)cc2)cnn1CCc1ccccc1

InChI Key: InChIKey=JYYVKRBENBOFNN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439391   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tumor necrosis factor receptor superfamily member 6


(Rattus norvegicus)
BDBM50439391
PNG
(CHEMBL2420401)
Show SMILES COC(=O)c1c(NC(=O)CSc2ccc(Br)cc2)cnn1CCc1ccccc1
Show InChI InChI=1S/C21H20BrN3O3S/c1-28-21(27)20-18(13-23-25(20)12-11-15-5-3-2-4-6-15)24-19(26)14-29-17-9-7-16(22)8-10-17/h2-10,13H,11-12,14H2,1H3,(H,24,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 513n/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of Fas-mediated cell death in oxygen and glucose deprived rat H9c2 cells treated 30 mins before oxygen and glucose deprivation measured af...


Bioorg Med Chem Lett 23: 5155-64 (2013)

More data for this
Ligand-Target Pair