BindingDB logo
myBDB logout

BDBM50439773 CHEMBL2419668

SMILES: COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccccc4F)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=OILXJIXXNSTPKM-FDALDRLYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439773   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50439773
PNG
(CHEMBL2419668)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccccc4F)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C33H35F2N5O4/c1-22-11-15-40(16-12-22)14-5-17-43-32-20-28-25(19-31(32)42-2)29(10-13-36-28)44-30-9-8-24(18-27(30)35)38-33(41)39-37-21-23-6-3-4-7-26(23)34/h3-4,6-10,13,18-22H,5,11-12,14-17H2,1-2H3,(H2,38,39,41)/b37-21+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.90n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using poly(Glu,Tyr) as substrate after 30 mins by HTRF assay


Bioorg Med Chem 21: 5246-60 (2013)


Article DOI: 10.1016/j.bmc.2013.06.026
BindingDB Entry DOI: 10.7270/Q28G8N52
More data for this
Ligand-Target Pair