BindingDB logo
myBDB logout

BDBM50439781 CHEMBL2419659

SMILES: COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccccc4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=IYXNXHLGJVXCTH-HPNXWYHWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439781   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50439781
PNG
(CHEMBL2419659)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccccc4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C33H36FN5O4/c1-23-12-16-39(17-13-23)15-6-18-42-32-21-28-26(20-31(32)41-2)29(11-14-35-28)43-30-10-9-25(19-27(30)34)37-33(40)38-36-22-24-7-4-3-5-8-24/h3-5,7-11,14,19-23H,6,12-13,15-18H2,1-2H3,(H2,37,38,40)/b36-22+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using poly(Glu,Tyr) as substrate after 30 mins by HTRF assay


Bioorg Med Chem 21: 5246-60 (2013)


Article DOI: 10.1016/j.bmc.2013.06.026
BindingDB Entry DOI: 10.7270/Q28G8N52
More data for this
Ligand-Target Pair