BDBM50439804 CHEMBL2419693::US9227982, 6

SMILES Oc1ccccc1CCC(=O)N(Cc1cccs1)Cc1nc2CCOCc2c(=O)[nH]1

InChI Key InChIKey=WGLKXYJVBRQOLA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439804   

TargetPoly [ADP-ribose] polymerase tankyrase-2 [959-1164](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50439804(CHEMBL2419693 | US9227982, 6)
Affinity DataIC50:  766nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439804(CHEMBL2419693 | US9227982, 6)
Affinity DataIC50:  3.77E+3nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1 [1112-1317](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50439804(CHEMBL2419693 | US9227982, 6)
Affinity DataIC50:  5.19E+3nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
In DepthDetails US Patent