BDBM50440284 CHEMBL2424780::US10457681, Compound Vesatolimod::US10487084, Compound Vesatolimod::US10508115, Compound Vesatolimod::US10654856, GS-9620::US10919895, Vesatolimod::US10981914, Compound Vesatolimod::US11242345, Example GS-9620::US9708325, GS-9620

SMILES: CCCCOc1nc(c2c(n1)N(CC(=O)N2)Cc3cccc(c3)CN4CCCC4)N

InChI Key: InChIKey=VFOKSTCIRGDTBR-UHFFFAOYSA-N

Data: 13 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50440284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	517	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.87E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	291	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Mouse)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50440284 (CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair