BDBM50440533 CHEMBL2426169

SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N

InChI Key InChIKey=OOCHZXDFBWHESO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440533   

TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50440533(CHEMBL2426169)
Affinity DataIC50:  300nMAssay Description:Inhibition of BLM (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase Q1(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50440533(CHEMBL2426169)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50440533(CHEMBL2426169)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of WRN (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed