BDBM50440659 CHEMBL2430358

SMILES CNC(=O)c1ccccc1Nc1cc(Nc2ccc(cc2OC)N2CCOCC2)ncc1C(F)(F)F

InChI Key InChIKey=IGUBBWJDMLCRIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440659   

TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50440659(CHEMBL2430358)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant GST-tagged FAK catalytic domain region (amino acids 411-686) (unknown origin) expressed in Sf9 cells after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50440659(CHEMBL2430358)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of GST-fused FAK (411 to 686 residues) (unknown origin) expressed in sf9 cells using poly(Glu:Tyr) (4:1) copolymer as substrate by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50440659(CHEMBL2430358)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of GST-FAK catalytic domain region (411-686) (unknown origin) expressed in baculovirus infected Sf9 cells by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed