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BDBM50440983 CHEMBL2431935

SMILES: OC(=O)c1ccc(cc1O)N(Cc1ccc(cc1)C1CCCCC1)C(=O)CN(Cc1c(F)c(F)c(F)c(F)c1F)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key: InChIKey=QSNAWJVQVYHZBG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440983   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Signal transducer and activator of transcription 3


(Homo sapiens (Human))
BDBM50440983
PNG
(CHEMBL2431935)
Show SMILES OC(=O)c1ccc(cc1O)N(Cc1ccc(cc1)C1CCCCC1)C(=O)CN(Cc1c(F)c(F)c(F)c(F)c1F)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C35H26F10N2O6S/c36-24-21(25(37)27(39)28(40)26(24)38)14-46(54(52,53)34-32(44)30(42)29(41)31(43)33(34)45)15-23(49)47(19-10-11-20(35(50)51)22(48)12-19)13-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h6-12,17,48H,1-5,13-15H2,(H,50,51)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



University of Toronto Mississauga

Curated by ChEMBL


Assay Description
Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...


J Med Chem 56: 7190-200 (2013)


Article DOI: 10.1021/jm3017255
BindingDB Entry DOI: 10.7270/Q24F1S6X
More data for this
Ligand-Target Pair