BDBM50441567 CHEMBL2436978::US10485800, Example 181

SMILES: CN1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CC1

InChI Key: InChIKey=QKKIWEILHCXECO-UHFFFAOYSA-N

Data: 31 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50441567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	591	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 2 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	661	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	731	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 9 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 10 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Protein delta homolog 1 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 11 (Mouse)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 11 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
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Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 11 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
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Protein delta homolog 1 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Sgk1 (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	201	n/a	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	217	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	257	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	307	n/a	n/a	n/a	n/a	n/a	n/a
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TRAF2 and NCK-interacting protein kinase (Human)	BDBM50441567 (CHEMBL2436978 | US10485800, Example 181) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
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