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BDBM50442457 CHEMBL2443115

SMILES: Cc1cccnc1CN1CCC2(CCN(C2=O)c2ccc(cc2)-c2ccc(CC(O)=O)cc2)CC1

InChI Key: InChIKey=CLRIWODPUANIKM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442457   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50442457
PNG
(CHEMBL2443115)
Show SMILES Cc1cccnc1CN1CCC2(CCN(C2=O)c2ccc(cc2)-c2ccc(CC(O)=O)cc2)CC1
Show InChI InChI=1S/C29H31N3O3/c1-21-3-2-15-30-26(21)20-31-16-12-29(13-17-31)14-18-32(28(29)35)25-10-8-24(9-11-25)23-6-4-22(5-7-23)19-27(33)34/h2-11,15H,12-14,16-20H2,1H3,(H,33,34)
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MMDB

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Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of PHD2 (unknown origin) by HTRF assay


Bioorg Med Chem 21: 6349-58 (2013)


Article DOI: 10.1016/j.bmc.2013.08.046
BindingDB Entry DOI: 10.7270/Q2K075Q1
More data for this
Ligand-Target Pair