BDBM50442531 11BETA-HYDROXYPROGESTERONE
SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C
InChI Key InChIKey=BFZHCUBIASXHPK-ATWVFEABSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50442531
Affinity DataEC50: 50nMAssay Description:Transactivation of wild-type human recombinant mineralocorticoid receptor expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of [1,2,-3H]-cortisone to [3H]cortisol preincubated for ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+4nMAssay Description:Transactivation of human recombinant mineralocorticoid receptor expressed in HEK-293 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair