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BDBM50442825 CHEMBL2440750

SMILES: CCCOC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1F

InChI Key: InChIKey=PNWBYIFLWUCWKS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442825   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM50442825
PNG
(CHEMBL2440750)
Show SMILES CCCOC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1F
Show InChI InChI=1S/C23H22FN3O3/c1-2-10-30-23(29)17-5-3-4-15(11-17)19-12-16(6-7-18(19)13-25)22(28)27-21-8-9-26-14-20(21)24/h3-9,11-12,14H,2,10,13,25H2,1H3,(H,26,27,28)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 5.10n/an/an/an/an/an/a



Amakem N.V.

Curated by ChEMBL


Assay Description
Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay


Bioorg Med Chem Lett 23: 6442-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.040
BindingDB Entry DOI: 10.7270/Q2BC411W
More data for this
Ligand-Target Pair