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BDBM50443294 CHEMBL3088220

SMILES: Cc1ncc(n1CC(=NNC(=O)c1ccc(O)cc1)c1ccc(Br)cc1)[N+]([O-])=O

InChI Key: InChIKey=XBPATCWTKVXDPF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443294   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50443294
PNG
(CHEMBL3088220)
Show SMILES Cc1ncc(n1CC(=NNC(=O)c1ccc(O)cc1)c1ccc(Br)cc1)[N+]([O-])=O
Show InChI InChI=1S/C19H16BrN5O4/c1-12-21-10-18(25(28)29)24(12)11-17(13-2-6-15(20)7-3-13)22-23-19(27)14-4-8-16(26)9-5-14/h2-10,26H,11H2,1H3,(H,23,27)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) autophosphorylation expressed in baculovirus infected insect Sf9 cel...


Bioorg Med Chem Lett 23: 6264-8 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.086
BindingDB Entry DOI: 10.7270/Q2FX7BWD
More data for this
Ligand-Target Pair