BDBM50443584 CHEMBL3091980

SMILES CN(C1C[C@@H]2CCCC[C@@H]2[C@H]1\C=C\c1ccc(cn1)-c1cccc(F)c1)S(C)(=O)=O

InChI Key InChIKey=BRSCNTKXIWSLQX-DKBLXCOBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443584   

TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50443584(CHEMBL3091980)
Affinity DataIC50:  97nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50443584(CHEMBL3091980)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50443584(CHEMBL3091980)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed