BDBM50444112 CHEMBL3093163

SMILES Nc1ncc(cc1-c1nc2ccc(Oc3cc(ccn3)C#N)cc2o1)-c1cnn(c1)C1CCNCC1

InChI Key InChIKey=MGTOXTLKZHLOTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50444112   

TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50444112(CHEMBL3093163)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of GRK-2 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50444112(CHEMBL3093163)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of GRK-5 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed