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BDBM50444431 CHEMBL3091628

SMILES: Cc1nc(Cc2cccc3ccccc23)c(\C=C\C(O)=O)c(C=O)c1O

InChI Key: InChIKey=WMQCLIDCYHPNTF-MDZDMXLPSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444431   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM50444431
PNG
(CHEMBL3091628)
Show SMILES Cc1nc(Cc2cccc3ccccc23)c(\C=C\C(O)=O)c(C=O)c1O
Show InChI InChI=1S/C21H17NO4/c1-13-21(26)18(12-23)17(9-10-20(24)25)19(22-13)11-15-7-4-6-14-5-2-3-8-16(14)15/h2-10,12,26H,11H2,1H3,(H,24,25)/b10-9+
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Similars

Article
PubMed
n/an/a 145n/an/an/an/an/an/a



Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...


Eur J Med Chem 70: 811-30 (2013)


Article DOI: 10.1016/j.ejmech.2013.10.026
BindingDB Entry DOI: 10.7270/Q2M61MQH
More data for this
Ligand-Target Pair