BDBM50444455 CHEBI:27924::Phenylhydrazine

SMILES NNc1ccccc1

InChI Key InChIKey=HKOOXMFOFWEVGF-UHFFFAOYSA-N

Data  6 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50444455   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50: >1.00E+6nMAssay Description:Tested for antagonist activity against NK1 receptor in rabbit vena cava by using substance P (SP) as agonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50:  200nMAssay Description:Inhibition of mouse IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed