BDBM50445879 CHEMBL3105672

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(c(s2)C(=O)c2cccc(F)c2)-c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=NAUYVLIMXBJFHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445879   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50445879(CHEMBL3105672)
Affinity DataIC50:  10nMAssay Description:Inhibition of APC-labeled RORgammat receptor ligand binding domain (unknown origin) after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Mus musculus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50445879(CHEMBL3105672)
Affinity DataIC50:  13nMAssay Description:Inhibition of RORgammat receptor ligand binding domain in mouse spleen CD4+ T cells assessed as inhibition of IL-17 production after 3 days by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed