BDBM50446537 CHEMBL3110100::US9505749, 106

SMILES: c1ccc2c(c1)C(=O)NC(=N2)SCCC(=O)NC3CCC(CC3)Oc4ccc(cc4)C#N

InChI Key: InChIKey=MCMCBDOVNWSRNM-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50446537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] (Human)	BDBM50446537 (CHEMBL3110100 | US9505749, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0973	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 [946-1162] (Human)	BDBM50446537 (CHEMBL3110100 | US9505749, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.57	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM50446537 (CHEMBL3110100 | US9505749, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Human)	BDBM50446537 (CHEMBL3110100 | US9505749, 106) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair