BDBM50446952 CHEMBL3115775

SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C

InChI Key InChIKey=XDSPQHGHALVRAI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50446952   

TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50446952(CHEMBL3115775)
Affinity DataIC50:  454nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in neutrophils assessed as inhibition of 5-oxo-ETE-induced cell migration after 2 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50446952(CHEMBL3115775)
Affinity DataIC50:  33nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50446952(CHEMBL3115775)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50446952(CHEMBL3115775)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50446952(CHEMBL3115775)
Affinity DataIC50:  2.73E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50446952(CHEMBL3115775)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50446952(CHEMBL3115775)
Affinity DataIC50:  2.73E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed