BDBM50447285 CHEMBL3113984

SMILES CC(O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1CC2(COC2)C1)S(=O)(=O)c1cccs1)C(F)(F)F

InChI Key InChIKey=HLKDUJBSZHOVJV-ZQRQZVKFSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447285   

TargetHexokinase-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50447285(CHEMBL3113984)
Affinity DataIC50:  524nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50447285(CHEMBL3113984)
Affinity DataEC50: >1.25E+4nMAssay Description:Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed