BDBM50447512 CHEMBL3115681

SMILES: CN1CCN(CC1)c2ccc(cc2)Nc3ncc4c(n3)N(C(=O)C(=C4)C#N)C5CCCC5

InChI Key: InChIKey=VADOZMZXXRBXNY-UHFFFAOYSA-N

Data: 21 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50447512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
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NUAK family SNF1-like kinase 1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 6/G1/S-specific cyclin-D1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73.5	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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NUAK family SNF1-like kinase 1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	272	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Human)	BDBM50447512 (CHEMBL3115681 | US20250129067, Compound ON123300) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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