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BDBM50447660 CHEMBL3112953

SMILES: Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cccnc4Cl)CC3)c2)cc1

InChI Key: InChIKey=RGYPCXSFVWHCPY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447660   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50447660
PNG
(CHEMBL3112953)
Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cccnc4Cl)CC3)c2)cc1
Show InChI InChI=1S/C26H26Cl2N4O2/c27-20-6-8-21(9-7-20)34-22-4-1-3-19(15-22)16-31-13-10-26(11-14-31)17-32(18-26)25(33)30-23-5-2-12-29-24(23)28/h1-9,12,15H,10-11,13-14,16-18H2,(H,30,33)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 247n/an/an/an/an/an/a



Janssen Research and Development LLC

Curated by ChEMBL


Assay Description
Inhibition of human FAAH after 60 mins


Bioorg Med Chem Lett 24: 737-41 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Rattus norvegicus (rat))
BDBM50447660
PNG
(CHEMBL3112953)
Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cccnc4Cl)CC3)c2)cc1
Show InChI InChI=1S/C26H26Cl2N4O2/c27-20-6-8-21(9-7-20)34-22-4-1-3-19(15-22)16-31-13-10-26(11-14-31)17-32(18-26)25(33)30-23-5-2-12-29-24(23)28/h1-9,12,15H,10-11,13-14,16-18H2,(H,30,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 225n/an/an/an/an/an/a



Janssen Research and Development LLC

Curated by ChEMBL


Assay Description
Inhibition of rat FAAH after 60 mins


Bioorg Med Chem Lett 24: 737-41 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP
More data for this
Ligand-Target Pair