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BDBM50447701 CHEMBL3113206

SMILES: Clc1ccc(cc1)S(=O)(=O)N1CCCc2ccc(Oc3cc(cc(=O)[nH]3)-c3nc(no3)C3CC3)cc12

InChI Key: InChIKey=PBFRNIOGCGCFEK-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447701   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50447701
PNG
(CHEMBL3113206)
Show SMILES Clc1ccc(cc1)S(=O)(=O)N1CCCc2ccc(Oc3cc(cc(=O)[nH]3)-c3nc(no3)C3CC3)cc12
Show InChI InChI=1S/C25H21ClN4O5S/c26-18-6-9-20(10-7-18)36(32,33)30-11-1-2-15-5-8-19(14-21(15)30)34-23-13-17(12-22(31)27-23)25-28-24(29-35-25)16-3-4-16/h5-10,12-14,16H,1-4,11H2,(H,27,31)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 mins


Bioorg Med Chem Lett 24: 1133-7 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.127
BindingDB Entry DOI: 10.7270/Q2445NZJ
More data for this
Ligand-Target Pair