BDBM50448494 CHEMBL3126657
SMILES COc1ccc2-c3c(C4CCCCC4)c4ccc(cc4n3CC3(CC3c2c1)C(=O)N1C2CC1CNC2)C(=O)NS(=O)(=O)N(C)C
InChI Key InChIKey=QQJQXOIBORDNRE-UHFFFAOYSA-N
Data 5 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50448494
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair