BDBM50448804 CHEMBL3128205

SMILES O=C1N(CCc2ccccc2)c2ccccc2C1=O

InChI Key InChIKey=XICVNIWRISOITG-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50448804   

TargetAldehyde dehydrogenase, dimeric NADP-preferring(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50448804(CHEMBL3128205)
Affinity DataIC50:  450nMAssay Description:Inhibition of full length human ALDH3A1 expressed in Escherichia coli BL21 (DE3) using benzaldehyde as substrate preincubated for 2 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetParkinson disease protein 7(Homo sapiens)
Tri-Institutional Phd Program In Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50448804(CHEMBL3128205)
Affinity DataIC50:  701nMAssay Description:Inhibition of pET3a-His-tagged DJ1 (unknown origin) expressed in Escherichia coli BL21 assessed as decrease in esterase activity using DiFMUAc as sub...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50448804(CHEMBL3128205)
Affinity DataIC50:  70nMAssay Description:Inhibition of human ALDH1A1 using propionaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50448804(CHEMBL3128205)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human ALDH2 using propionaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed