BDBM50448982 CHEMBL3125728
SMILES COc1ccc(cc1)-c1nc2ncc(cc2[nH]1)-c1csc(c1)C(=O)NCCC(C)C
InChI Key InChIKey=TVWMRPWVPSKLOP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50448982
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of IKK-epsilon (unknown origin) using 5FAM-AKELDQGSLCTpSFVGTLQ-NH2 as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of aurora B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of TBK1 in HEK293 cells after 4.5 hrs by ISRE-luciferase reporter gene assay in presence of poly I:CMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant full-length TBK1 (unknown origin) using CK1tide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair