BDBM50449038 CHEMBL3126204::US9212144, 15 (Ex. 17)

SMILES: c1cc(cc(c1)Cl)CCNCCc2ccc3ccc(nc3c2)N

InChI Key: InChIKey=LTZZOZXCYRCKFV-UHFFFAOYSA-N

Data: 47 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 47 hits for monomerid = 50449038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, brain (Rat)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		66	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
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Nitric oxide synthase, brain (Rat)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Rat)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Nitric oxide synthase, brain (Rat)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Nitric oxide synthase, brain (Rat)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rat)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 5A (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1E (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Nociceptin receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1F (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		440	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bovine)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		7.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bovine)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		7.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bovine)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		7.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bovine)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		7.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Human)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50449038 (CHEMBL3126204 | US9212144, 15 (Ex. 17)) Show SMILES Show InChI	GoogleScholar	UniChem		2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
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					More data for this Ligand-Target Pair