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BDBM50449040 CHEMBL3126208

SMILES: Nc1ccc2cc(CCNCCCc3cccc(F)c3)ccc2n1

InChI Key: InChIKey=YECAQWKNRAVMDE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50449040   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric-oxide synthase, brain


(Rattus norvegicus (rat))
BDBM50449040
PNG
(CHEMBL3126208)
Show SMILES Nc1ccc2cc(CCNCCCc3cccc(F)c3)ccc2n1
Show InChI InChI=1S/C20H22FN3/c21-18-5-1-3-15(14-18)4-2-11-23-12-10-16-6-8-19-17(13-16)7-9-20(22)24-19/h1,3,5-9,13-14,23H,2,4,10-12H2,(H2,22,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.37E+3n/an/an/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant nNOS expressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture assay


J Med Chem 57: 1513-30 (2014)


Article DOI: 10.1021/jm401838x
BindingDB Entry DOI: 10.7270/Q2MP54SZ
More data for this
Ligand-Target Pair