BDBM50449062 CHEMBL3126943
SMILES Cc1ccccc1C(C)(C)CC(O)(Cc1cc2ncncc2[nH]1)C(F)(F)F
InChI Key InChIKey=YODZJEXOVOLTHE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50449062
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >2.00E+3nMAssay Description:Competitive binding affinity to progesterone receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence polar...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Competitive binding affinity to mineralocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence ...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Transrepression activity at glucocorticoid receptor in human fibroblasts assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair