BDBM50449237 CHEMBL3128141

SMILES CC1(C)OC(=O)c2c1ccnc2NCc1ccccc1

InChI Key InChIKey=VXLRPUBURYXJIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449237   

TargetProteasome subunit beta type-1(Homo sapiens (Human))
Yerevan State University

Curated by ChEMBL
LigandPNGBDBM50449237(CHEMBL3128141)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of 20s proteasome beta 1 subunit caspase-like activity in human HeLa cells using Z-nLPnLD as substrate after 17 hrs by chemiluminescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Yerevan State University

Curated by ChEMBL
LigandPNGBDBM50449237(CHEMBL3128141)
Affinity DataIC50:  600nMAssay Description:Inhibition of 20s immunoproteasome beta 1 subunit caspase-like activity in human blood monocytes using Z-LLE-betaNA as substrate at 2 uM preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed