BDBM50450446 CHEMBL4176829

SMILES Oc1c(cc(c2cccnc12)S(=O)(=O)C1CCCC1)C(F)(F)F

InChI Key InChIKey=MXZPWFQESQPBKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450446   

TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50450446(CHEMBL4176829)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50450446(CHEMBL4176829)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of c-terminal hexa-His tagged human S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed