BDBM50450813 Atripla::CHEBI:63625::GS-1275::PMP-A::Tenofovir::Truvada::US12049474, Compound TFV

SMILES: C[C@H](Cn1cnc2c1ncnc2N)OCP(=O)(O)O

InChI Key: InChIKey=SGOIRFVFHAKUTI-UHFFFAOYSA-N

Data: 9 IC50  1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50450813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicase polyprotein 1ab (SARS-CoV)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Capsid protein (HBV)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	242	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50450813 (CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair