BDBM50451695 CHEMBL4217576

SMILES COCc1ccc(CNC(=O)c2sc(Br)c3CC(C)(C)CCc23)cc1

InChI Key InChIKey=LAYLVIDKHAQDFA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451695   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451695(CHEMBL4217576)
Affinity DataIC50:  460nMAssay Description:Inhibition of recombinant human Cav3.1 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 20 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451695(CHEMBL4217576)
Affinity DataIC50:  470nMAssay Description:Inhibition of recombinant human Cav3.2 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 20 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451695(CHEMBL4217576)
Affinity DataIC50:  350nMAssay Description:Inhibition of recombinant human Cav3.3 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 20 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed