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BDBM50451770 CHEMBL350614

SMILES: Clc1cccc(CNC(=N)\C=C\c2ccccc2)c1Cl

InChI Key: InChIKey=NJOJLSWUQNMZBT-MDZDMXLPSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50451770   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Homo sapiens (Human))
BDBM50451770
PNG
(CHEMBL350614)
Show SMILES Clc1cccc(CNC(=N)\C=C\c2ccccc2)c1Cl
Show InChI InChI=1S/C16H14Cl2N2/c17-14-8-4-7-13(16(14)18)11-20-15(19)10-9-12-5-2-1-3-6-12/h1-10H,11H2,(H2,19,20)/b10-9+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.60n/an/an/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]ifenprodil binding to recombinant human NR1a/NR2B receptors expressed in L(tk-) cells


Bioorg Med Chem Lett 13: 693-6 (2003)


Article DOI: 10.1016/s0960-894x(02)01060-0
BindingDB Entry DOI: 10.7270/Q2KK9D95
More data for this
Ligand-Target Pair