BDBM50452810 CHEMBL4207135

SMILES OC(c1ccc2N(CCSc2c1)S(=O)(=O)c1ccccc1F)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=RQRZPMXVSVHBGG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452810   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452810(CHEMBL4207135)
Affinity DataEC50:  1.26E+3nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed