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BDBM50452913 CHEMBL4217985

SMILES: Oc1ccccc1C(=O)N1CCN(Cc2ccc(F)cc2)CC1

InChI Key: InChIKey=GRMGIEGXDXUPSI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50452913
PNG
(CHEMBL4217985)
Show SMILES Oc1ccccc1C(=O)N1CCN(Cc2ccc(F)cc2)CC1
Show InChI InChI=1S/C18H19FN2O2/c19-15-7-5-14(6-8-15)13-20-9-11-21(12-10-20)18(23)16-3-1-2-4-17(16)22/h1-8,22H,9-13H2
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.06E+3n/an/an/an/an/an/a



Universit� di Messina

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate preincubated with substrate for 10 mins followed by protein addition...


J Med Chem 61: 3908-3917 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01745
BindingDB Entry DOI: 10.7270/Q2V127DR
More data for this
Ligand-Target Pair