BindingDB logo
myBDB logout

BDBM50452929 CHEMBL287093

SMILES: CN1CC2CCC1C(C2)c1nc(no1)-c1cn(C)c2ccccc12

InChI Key: InChIKey=UKSLIIXPJZIKSV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452929   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452929
PNG
(CHEMBL287093)
Show SMILES CN1CC2CCC1C(C2)c1nc(no1)-c1cn(C)c2ccccc12
Show InChI InChI=1S/C19H22N4O/c1-22-10-12-7-8-17(22)14(9-12)19-20-18(21-24-19)15-11-23(2)16-6-4-3-5-13(15)16/h3-6,11-12,14,17H,7-10H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 85n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452929
PNG
(CHEMBL287093)
Show SMILES CN1CC2CCC1C(C2)c1nc(no1)-c1cn(C)c2ccccc12
Show InChI InChI=1S/C19H22N4O/c1-22-10-12-7-8-17(22)14(9-12)19-20-18(21-24-19)15-11-23(2)16-6-4-3-5-13(15)16/h3-6,11-12,14,17H,7-10H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 224n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair