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BDBM50452960 CHEMBL286001

SMILES: Cc1ccc2n(C)cc(-c3noc(n3)C3CN4CCC3CC4)c2c1

InChI Key: InChIKey=JMTFDRWDVZMGQA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452960   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452960
PNG
(CHEMBL286001)
Show SMILES Cc1ccc2n(C)cc(-c3noc(n3)C3CN4CCC3CC4)c2c1
Show InChI InChI=1S/C19H22N4O/c1-12-3-4-17-14(9-12)16(10-22(17)2)18-20-19(24-21-18)15-11-23-7-5-13(15)6-8-23/h3-4,9-10,13,15H,5-8,11H2,1-2H3
PDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 331n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair