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BDBM50452961 CHEMBL37802

SMILES: C1CN2CCC1C(C2)c1nc(no1)-c1c[nH]c2ccccc12

InChI Key: InChIKey=OOLMZOZIHGDVNF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452961   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50452961
PNG
(CHEMBL37802)
Show SMILES C1CN2CCC1C(C2)c1nc(no1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C17H18N4O/c1-2-4-15-12(3-1)13(9-18-15)16-19-17(22-20-16)14-10-21-7-5-11(14)6-8-21/h1-4,9,11,14,18H,5-8,10H2
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.70n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.


J Med Chem 34: 140-51 (1991)


Article DOI: 10.1021/jm00105a021
BindingDB Entry DOI: 10.7270/Q2DV1MD5
More data for this
Ligand-Target Pair