BindingDB logo
myBDB logout

BDBM50453183 CHEMBL2114060

SMILES: CN1CC2CC1C[C@H]2OC(=O)C(C)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=GVNGZGPVJXWAOP-RRWXTXHCSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453183   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50453183
PNG
(CHEMBL2114060)
Show SMILES CN1CC2CC1C[C@H]2OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-22(17-9-5-3-6-10-17,18-11-7-4-8-12-18)21(24)25-20-14-19-13-16(20)15-23(19)2/h3-12,16,19-20H,13-15H2,1-2H3/t16?,19?,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.423n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell


J Med Chem 35: 2184-91 (1992)


Article DOI: 10.1021/jm00090a006
BindingDB Entry DOI: 10.7270/Q2B27T74
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50453183
PNG
(CHEMBL2114060)
Show SMILES CN1CC2CC1C[C@H]2OC(=O)C(C)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H25NO2/c1-22(17-9-5-3-6-10-17,18-11-7-4-8-12-18)21(24)25-20-14-19-13-16(20)15-23(19)2/h3-12,16,19-20H,13-15H2,1-2H3/t16?,19?,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.522n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell


J Med Chem 35: 2184-91 (1992)


Article DOI: 10.1021/jm00090a006
BindingDB Entry DOI: 10.7270/Q2B27T74
More data for this
Ligand-Target Pair