BDBM50453573 CHEMBL352591

SMILES Oc1ccc(O)c(\C=N\c2ccc(O)c(CC(=O)NOCc3ccccc3)c2)c1

InChI Key InChIKey=NQSXLQDSUVJXKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453573   

TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50453573(CHEMBL352591)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50453573(CHEMBL352591)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of EGF-stimulated DNA synthesis in ER 22 (EGF-receptor expressing) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed