BDBM50453821 CHEMBL4206831

SMILES: CCC(=O)Nc1ccc(cc1)C(=O)Nc2ccc(cc2)Nc3ncc4c(n3)N(c5ccc(cc5C(=O)N4C)C)C

InChI Key: InChIKey=KGXBCWANASZZQG-UHFFFAOYSA-N

Data: 6 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50453821   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Human)	BDBM50453821 (CHEMBL4206831) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50453821 (CHEMBL4206831) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50453821 (CHEMBL4206831) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50453821 (CHEMBL4206831) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
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Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM50453821 (CHEMBL4206831) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	714	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 (Human)	BDBM50453821 (CHEMBL4206831) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM50453821 (CHEMBL4206831) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK4 (Human)	BDBM50453821 (CHEMBL4206831) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
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