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BDBM50454015 CHEMBL144921

SMILES: COCOc1c(cccc1-c1ccc(cc1)C(=O)OCC(C)CC(C)(C)C)-c1ccccc1

InChI Key: InChIKey=XZCBWCFFMKCRKN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454015   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50454015
PNG
(CHEMBL144921)
Show SMILES COCOc1c(cccc1-c1ccc(cc1)C(=O)OCC(C)CC(C)(C)C)-c1ccccc1
Show InChI InChI=1S/C29H34O4/c1-21(18-29(2,3)4)19-32-28(30)24-16-14-23(15-17-24)26-13-9-12-25(27(26)33-20-31-5)22-10-7-6-8-11-22/h6-17,21H,18-20H2,1-5H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
In vitro inhibition of EGF-stimulated DNA synthesis of ER 22 cells by following the incorporation of methyl-[3H]thymidine.


J Med Chem 38: 4693-703 (1995)


Article DOI: 10.1021/jm00023a009
BindingDB Entry DOI: 10.7270/Q2FX78G6
More data for this
Ligand-Target Pair