BDBM50455500 CHEMBL4207924

SMILES: CCC1CN(Cc2ccccc2)c2cc(ccc2N1C(C)=O)-c1cccc(c1)C(N)=O

InChI Key: InChIKey=LRSBCNAWSPLFLL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50455500 (CHEMBL4207924) Show SMILES CCC1CN(Cc2ccccc2)c2cc(ccc2N1C(C)=O)-c1cccc(c1)C(N)=O Show InChI InChI=1S/C26H27N3O2/c1-3-23-17-28(16-19-8-5-4-6-9-19)25-15-21(12-13-24(25)29(23)18(2)30)20-10-7-11-22(14-20)26(27)31/h4-15,23H,3,16-17H2,1-2H3,(H2,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Displacement of (+)-JQ1 from 6H-Thr BRD4 Y97A mutant BD2 (unknown origin) after 30 mins by TR-FRET assay				J Med Chem 61: 4317-4334 (2018) Article DOI: 10.1021/acs.jmedchem.7b01666 BindingDB Entry DOI: 10.7270/Q27H1N6W
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50455500 (CHEMBL4207924) Show SMILES CCC1CN(Cc2ccccc2)c2cc(ccc2N1C(C)=O)-c1cccc(c1)C(N)=O Show InChI InChI=1S/C26H27N3O2/c1-3-23-17-28(16-19-8-5-4-6-9-19)25-15-21(12-13-24(25)29(23)18(2)30)20-10-7-11-22(14-20)26(27)31/h4-15,23H,3,16-17H2,1-2H3,(H2,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assay				J Med Chem 61: 4317-4334 (2018) Article DOI: 10.1021/acs.jmedchem.7b01666 BindingDB Entry DOI: 10.7270/Q27H1N6W
					More data for this Ligand-Target Pair